Hepatocyte glutathione s-transferase mu 2
WebThis gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. WebWilliams’ E medium (Sigma-Aldrich, Mu¨nchen, Germany); fetal bovine serum (European Commission approved, South American origin), L -glutamine, hu- man serum type AB, penicillin/streptomycin ...
Hepatocyte glutathione s-transferase mu 2
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WebBoth acrylonitrile and its primary metabolite, 2-cyanoethylene oxide, also react with glutathione. To better understand the role of glutathione in the manifestation of … Webab53942 has been referenced in 8 publications. Kano SI et al. Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. …
Web23 jan. 2007 · Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13 (S),14 (S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions ( PubMed: 27791009 ). 3 publications Catalytic activity Web6 apr. 2024 · Glutathione-S-transferase mu 2 (GSTM2), as a member of phase II drug metabolizing enzymes (DMEs), regulates cellular antioxidant and detoxificant. …
Web22 aug. 2024 · Liver sections were deparaffinized in xylene, rehydrated in a graded alcohol series, and blocked with 3% H 2 O 2 or 5% bovine serum albumin in methanol for 10–30 min. Tissue sections were washed with phosphate buffer solution and then immunostained with primary antibodies for glutathione S-transferase-Pi (GST-Pi) and 8-hydroxy-2′ … WebHere, glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase mu 4 (GSTM4) proteins (reduced in the SG2 vs. EV clones) are nodes of three different …
Web1 sep. 2016 · Serum alanine and aspartate aminotransferases (ALT/AST) have been the gold standard for detection and quantification of liver injury for over 6 decades, but have …
Web22 sep. 2024 · Glutathione S-tranferases (GSTs) are phase II drug metabolizing enzymes, they play crucial role in detoxification of environmental pollutants, carcinogens, drugs, xenobiotics and oxidative... boston house data setWeb2. 2024. 01-2024.12 广东药科大学中医药研究院 教授、硕士生导师 ... Rong X, Guo J*; Hepatocyte glutathione S-transferase mu 2 prevents non-alcoholic steatohepatitis by … boston house eye unitWeb摘要 Alzheimer's disease(AD)is affected by genetic factors.Polymorphisms in the glutathione S-transfe rase omega-1(Gsto1)gene have been shown by genetic correlation analyses performed in different ethnic populations to be genetic risk factors for AD.Gene expression profile data from BXD recombinant inbred mice were used in combination … boston house dcWebProtein target information for Glutathione S-transferase Mu 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay … boston house condoWebWhen liver cells are exposed to large concentrations of dangerous substances, hepatocyte malfunction, membrane damage, ... catalase, and glutathione-S-transferase, and … boston house dataset csvWeb22 sep. 2024 · Adv. Anim. Vet. Sci February 24, 2024. Disturbance of the biomarkers in hepato and nephrotoxicity that induced by acrylamide (ACR) were studied in rat. ACR … boston house eastbourneWeb14 okt. 2024 · DOI: 10.1016/j.jhep.2024.09.040 Corpus ID: 239018721; Hepatocyte glutathione S-transferase mu 2 prevents non-alcoholic steatohepatitis by suppressing … boston house consulting