2024 Gm-csf protein

Gm-csf protein

Author: ardb

August undefined, 2024

WebGene summary (Entrez)i. Useful information about the gene from Entrez. The protein encoded by this gene is a cytokine that controls the production, differentiation, and … WebApr 9, 2024 · We have successfully cloned and stably integrated murine GM-CSF into HEK293T cells, which consistently secrete 180 ng/ml of GM-CSF . GM-CSF protein size is predicted to be ~16 kDa. Our sup-GM-CSF runs as a single band in the supernatant at approximately 17 kDa. Purified GM-CSF obtained from biolegend runs at a smaller size …

GM-CSF Products: R&D Systems

WebGM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils. Recombinant mouse GM-CSF is a 14.0 kDa protein containing 125 amino acid residues. WebIn this study, two strains of the yeast P. pastoris were constructed, one of which produced authentic recombinant human granulocyte-macrophage colony-stimulating factor (ryGM-CSF), and the other was a chimera consisting of ryGM-CSF genetically fused with mature human apolipoprotein A-I (ApoA-I) (ryGM-CSF-ApoA-I). Both forms of the cytokine were … adozione figlio marito

Role of GM-CSF in regulating metabolism and mitochondrial …

http://www.emro.who.int/imemrf/Iran_J_Pediatr/Iran_J_Pediatr_2009_19_3_213.pdf Webform of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is … WebMature porcine GM-CSF shares 61%-72% amino acid sequence identity with canine, feline, human, and rat GM-CSF and 53% with mouse GM-CSF. GM-CSF exerts its biological effects through a heterodimeric receptor complex composed of GM-CSF R alpha /CD116 and the signal transducing common beta chain (CD131) which is also a component of … js ループ終了

UniProt

WebGM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found ... WebGM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, … adozione figlio maggiorenneWebGM-CSF is a proinflammatory cytokine with neuroprotective and angiogenic properties exhibited during in vivo models of cerebral ischemia . In vitro, GM-CSF promotes macrophage, neutrophil and eosinophil survival and activation . Of note, GM-CSF was shown to promote arteriogenesis in cardiovascular ischemic disease, thereby … jsレネップバーデンバーデン

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Gm-csf protein

Recombinant Human GM-CSF carrier-free - BioLegend

WebThe new PVAX1-IRES-GM/B7.1 vector was successfully modified with the GM-CSF and B7.1 molecular adjuvants via IRES linking. 38 The use of IRESs enables vectors to … WebRecombinant Mouse GM-CSF (Catalog # 415-ML) stimulates cell proliferation of the DA3 mouse myeloma cell line. The ED 50 for this effect is 5-30 pg/mL. SDS-PAGE View Larger 1 μg/lane of Recombinant Mouse GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.

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WebFeb 13, 2006 · It is secreted as a monomeric 23 kDa glycosylated small protein. Mature murine GM-CSF has 124 residues and human has 127 residues; both are derived from a precursor containing a signal peptide 6 ... WebGM-CSF: Products. GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the …

http://www.emro.who.int/imemrf/Iran_J_Pediatr/Iran_J_Pediatr_2009_19_3_213.pdf WebGranulocyte-macrophage colony-stimulating factor (GM-CSF) is a small glycoprotein growth factor which stimulates the production and function of neutrophils, eosinophils and monocytes.

WebIt is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM‑CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. WebThe new PVAX1-IRES-GM/B7.1 vector was successfully modified with the GM-CSF and B7.1 molecular adjuvants via IRES linking. 38 The use of IRESs enables vectors to produce multiple products from a single transcriptional unit, thus eliminating the loss of gene expression caused by promoter competition or counterselection. 39 Thus, when the sig ...

WebProduct Details Source Human GM-CSF, amino acids Ala18- Glu144 (Accession# NM_000758) was expressed in E. coli. Molecular Mass The 127 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 14477.5 Da.

WebRecombinant Human GM-CSF (Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor; rHuGM-CSF)；重组人粒细胞-巨噬细胞集落刺激因子 ... 而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。 js レンダリング遅いWebAchieve higher consistency and quality standards with a premium grade bioactive protein. Recombinant mouse GM-CSF protein (Active) (ab259385) High batch-to-batch … adozione gatti rossiWebActive Recombinant human GM-CSF protein (Active) is a HEK 293 Full length protein 18 to 144 aa range animal free, >=95% purity, <= 0.005 Eu/µg endotoxin level and validated in FuncS, SDS-PAGE… adozione gattini firenzeWebMay 4, 2024 · GM-CSF supports more myeloid progenitor cells, whereas IL-3 promotes more erythroid, megakaryocytic and multipotential progenitor cells. Their complementary in vivo biological effects and cross competition for receptor binding prompted the development of PIXY321, a synthetic hybrid protein of GM-CSF and IL-3. jsレネップはなれWebGM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N ... adozione gattini romaWebRecombinant Human GM-CSF/CSF2 Protein (Met1-Glu144) 10015-HNAH is expressed in HEK293 Cells. With high purity, high biological activity, high stability, and other superior features, you can use this Human GM-CSF/CSF2 protein for … jsレネップ有楽町WebUsed in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous … js ログ